Savanna Journal of Basic and Applied Sciences 7(2):174-181
Toxicological Assessment of Okra Varieties (Clemson spineless, Ex-Samaru, and NHAE-74) in Wistar Rats
Abba A. , Umar K.J. , Hassan L.G. , Yakubu M.K. , Adamu Y. , Umar A. AliyuA. , and Bunza M.S.
ABSTRACT
Since plants make up the majority of the food consumed by living things, their metabolisms generate a variety of
poisons that can cause illness and occasionally even death. In order to determine the safety of three improved okra
seed variants, this journal assesses their toxicity. Twenty-eight albino rats weighing between 132 and 136 g were split
into four groups at random for the investigation. For twenty-eight days, group 1 (control) was fed their regular diet of
chicken feed, while groups 2, 3, and 4 were fed a mixture of a 1:3 ratio of chicken feed and (75% okra seed), a variety
of okra seed (Clemson spineless, Ex-samaru, and NHAE-74, respectively). The mass difference of each rat was
measured at the end of each seven days. After twenty-eight days, the rats were killed and their blood was extracted by
cardiac puncture. The kidney function parameters, creatinine, urea, Na+, K+, Cl-, and HCO3- are within their normal
range. The liver function parameter of Total protein (3–6.5), albumin (2.87–2.93), and globulin (2.23-2.85)
concentrations (g/dL) are all within the normal range. The levels of direct bilirubin (0.14-0.17), total bilirubin (0.39
0.43), and AST, ALT, and ALP (mg/dL) are all within the normal range. In haematological studies, every parameter
that was examined fell within the normal range. The seeds are safe to eat because feeding on them causes an increase
in body weight without causing anaemia, kidney, or liver problems.
